SP475CLINICAL BENEFITS OF PRE-DILUTION ON-LINE HEMODIAFILTRATION AS COMPARED TO HEMODIALYSIS WITH A SUPER-HIGH-FLUX DIALYZER

Survival Benefit of Hemodiafiltration Compared With Prolonged High-flux Hemodialysis.

INTRODUCTION  Patients on dialysis have a high rate of death, mainly of cardiovascular cause. Nephrologists are actively looking for ways to improve patients' outcomes, and alternative dialysis strategies, such as long conventional hemodialysis and hemodiafiltration, are currently being investigated. The aim of this study was to compare anemia, nutrition, inflammation, mineral metabolism, and 3...

Mid-Dilution Hemodiafiltration Compared to Pre- and Post-Dilution Hemodiafiltration: A Study Preparatory to a Prospective Randomized Trial

A comparison of on-line hemodiafiltration and high-flux hemodialysis: a prospective clinical study.

Some of the morbidity associated with chronic hemodialysis is thought to result from retention of large molecular weight solutes that are poorly removed by diffusion in conventional hemodialysis. Hemodiafiltration combines convective and diffusive solute removal in a single therapy. The hypothesis that hemodiafiltration provides better solute removal than high-flux hemodialysis was tested in a ...

Cost-effectiveness analysis of online hemodiafiltration versus high-flux hemodialysis

BACKGROUND Clinical studies suggest that hemodiafiltration (HDF) may lead to better clinical outcomes than high-flux hemodialysis (HF-HD), but concerns have been raised about the cost-effectiveness of HDF versus HF-HD. Aim of this study was to investigate whether clinical benefits, in terms of longer survival and better health-related quality of life, are worth the possibly higher costs of HDF ...

Effects of Hemodiafiltration and High Flux Hemodialysis on Nerve Excitability in End-Stage Kidney Disease

OBJECTIVES Peripheral neuropathy is the most common neurological complication in end-stage kidney disease. While high flux hemodialysis (HFHD) and hemodiafiltration (HDF) have become the preferred options for extracorporeal dialysis therapy, the effects of these treatments on nerve excitability have not yet been examined. METHODS An observational proof-of-concept study of nerve excitability a...